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The role of distinct co-mutation patterns with TP53 mutation in immunotherapy for NSCLC

TP53 mutations was reported to be correlated to the efficacy of program death-1 (PD-1) and program death ligand-1 (PD-L1). The role of co-mutations of TP53 with other recurrently mutated genes in outcome of anti-PD-(L)1 treatment for non-small cell lung cancer (NSCLC) is unknown. Here we mined a pre...

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Detalles Bibliográficos
Autores principales: Wang, Shuhang, Jiang, Miaomiao, Yang, Zuozhen, Huang, Xiaoyun, Li, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720680/
https://www.ncbi.nlm.nih.gov/pubmed/35005121
http://dx.doi.org/10.1016/j.gendis.2020.04.001