Tsc2 mutation induces renal tubular cell nonautonomous disease

TSC renal cystic disease is poorly understood and has no approved treatment. In a new principal cell-targeted murine model of Tsc cystic disease, the renal cystic epithelium is mostly composed of type A intercalated cells with an intact Tsc2 gene confirmed by sequencing, although these cells exhibit...

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Detalles Bibliográficos
Autores principales: Kumar, Prashant, Zadjali, Fahad, Yao, Ying, Johnson, Daniel, Siroky, Brian, Astrinidis, Aristotelis, Vogel, Peter, Gross, Kenneth W., Bissler, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2021
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720703/
https://www.ncbi.nlm.nih.gov/pubmed/35005118
http://dx.doi.org/10.1016/j.gendis.2021.03.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720703/
https://www.ncbi.nlm.nih.gov/pubmed/35005118
http://dx.doi.org/10.1016/j.gendis.2021.03.010

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