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Critical roles of FTO-mediated mRNA m6A demethylation in regulating adipogenesis and lipid metabolism: Implications in lipid metabolic disorders

The goal this review is to clarify the effects of the fat mass and obesity-associated protein (FTO) in lipid metabolism regulation and related underlying mechanisms through the FTO-mediated demethylation of m(6)A modification. FTO catalyzes the demethylation of m(6)A to alter the processing, maturat...

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Detalles Bibliográficos
Autores principales: Yang, Zhou, Yu, Guang-li, Zhu, Xiao, Peng, Tian-hong, Lv, Yun-cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720706/
https://www.ncbi.nlm.nih.gov/pubmed/35005107
http://dx.doi.org/10.1016/j.gendis.2021.01.005