mtROS Induced via TLR-2-SOCE Signaling Plays Proapoptotic and Bactericidal Role in Mycobacterium fortuitum-Infected Head Kidney Macrophages of Clarias gariepinus

The mechanisms underlying Mycobacterium fortuitum-induced mycobacteriosis remain unexplored. Using head kidney macrophages (HKM) from catfish (Clarias gariepinus), we report that Ca(2+) surge across mitochondrial-Ca(2+) uniporter (MICU), and consequent mitochondrial ROS (mtROS) production, is impera...

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Detalles Bibliográficos
Autores principales: Dahiya, Priyanka, Hussain, Md. Arafat, Mazumder, Shibnath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720869/
https://www.ncbi.nlm.nih.gov/pubmed/34987503
http://dx.doi.org/10.3389/fimmu.2021.748758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720869/
https://www.ncbi.nlm.nih.gov/pubmed/34987503
http://dx.doi.org/10.3389/fimmu.2021.748758

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