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DNA methylation and hydroxymethylation analysis using a high throughput and low bias direct injection mass spectrometry platform

DNA modifications are small covalent chemical groups that modify nucleotides to regulate DNA readout. Anomalous abundance and genome-wide localization of these modifications can negatively tune gene expression and propagate into unbalanced epigenetics regulation, which is known to be associated with...

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Detalles Bibliográficos
Autores principales: Sun, Yan, Stransky, Stephanie, Aguilan, Jennifer, Brenowitz, Michael, Sidoli, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720912/
https://www.ncbi.nlm.nih.gov/pubmed/35004218
http://dx.doi.org/10.1016/j.mex.2021.101585