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DNA methylation and hydroxymethylation analysis using a high throughput and low bias direct injection mass spectrometry platform
DNA modifications are small covalent chemical groups that modify nucleotides to regulate DNA readout. Anomalous abundance and genome-wide localization of these modifications can negatively tune gene expression and propagate into unbalanced epigenetics regulation, which is known to be associated with...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720912/ https://www.ncbi.nlm.nih.gov/pubmed/35004218 http://dx.doi.org/10.1016/j.mex.2021.101585 |