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The concentration of brain homogenates with the Amicon Ultra Centrifugal filters

Accurately measuring the brain concentration of a neurotherapeutic is critical in determining its pharmacokinetic profile in vivo. Biologics are potential therapeutics for neurologic diseases and biologics fused to an antibody targeting a transcytosis receptor at the Blood-Brain Barrier, designated...

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Detalles Bibliográficos
Autores principales: Yang, Joshua, Sumbria, Rachita K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720913/
https://www.ncbi.nlm.nih.gov/pubmed/35004217
http://dx.doi.org/10.1016/j.mex.2021.101584