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Stressor-Induced “Inflammaging” of Vascular Smooth Muscle Cells via Nlrp3-Mediated Pro-inflammatory Auto-Loop

Calcification of the vessel wall as one structural pathology of aged vessels is associated with high cardiovascular mortality of elderly patients. Aging is linked to chronic sterile inflammation and high burden of reactive oxygen species (ROS), leading to activation of pattern recognition receptors...

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Detalles Bibliográficos
Autores principales: Herrmann, Jaqueline, Xia, Mengdi, Gummi, Manasa Reddy, Greco, Anna, Schacke, Annika, van der Giet, Markus, Tölle, Markus, Schuchardt, Mirjam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720922/
https://www.ncbi.nlm.nih.gov/pubmed/34988126
http://dx.doi.org/10.3389/fcvm.2021.752305