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Hydroxychloroquine administration exacerbates acute kidney injury complicated by lupus nephritis

BACKGROUND: Hydroxychloroquine (HCQ) has been recommended as a basic treatment for lupus nephritis (LN) during this decade based on its ability to improve LN-related renal immune-mediated inflammatory lesions. As a classical lysosomal inhibitor, HCQ may inhibit lysosomal degradation and disrupt prot...

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Detalles Bibliográficos
Autores principales: An, Ning, Yang, Chen, Wu, Hong-Luan, Guo, Yun, Huang, Xi-Jie, Huang, Tong-Sheng, Wu, Zhi-Hong, Xue, Jing, Chen, Rui-Hong, Li, Zhi-Hang, Pan, Qing-Jun, Liu, Hua-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720942/
https://www.ncbi.nlm.nih.gov/pubmed/34980245
http://dx.doi.org/10.1186/s13075-021-02700-x