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High-Salt Attenuates the Efficacy of Dapagliflozin in Tubular Protection by Impairing Fatty Acid Metabolism in Diabetic Kidney Disease

High-salt intake leads to kidney damage and even limits the effectiveness of drugs. However, it is unclear whether excessive intake of salt affects renal tubular energy metabolism and the efficacy of dapagliflozin on renal function in diabetic kidney disease (DKD). In this study, we enrolled 350 DKD...

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Detalles Bibliográficos
Autores principales: Zou, Meina, Chen, Yanrong, Zheng, Zongji, Sheng, Shuyue, Jia, Yijie, Wang, Xiangyu, Ren, Shijing, Yang, Yanling, Li, Xiaomin, Dong, Wenhui, Guan, Meiping, Zhang, Qian, Xue, Yaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720966/
https://www.ncbi.nlm.nih.gov/pubmed/34987387
http://dx.doi.org/10.3389/fphar.2021.741087