Mfn2 Regulates High Glucose-Induced MAMs Dysfunction and Apoptosis in Podocytes via PERK Pathway

The endoplasmic reticulum (ER) stress and mitochondrial dysfunction in high glucose (HG)-induced podocyte injury have been demonstrated to the progression of diabetic kidney disease (DKD). However, the pathological mechanisms remain equivocal. Mitofusin2 (Mfn2) was initially identified as a dynamin-...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Yun, Chen, Zhaowei, Hu, Jijia, Feng, Jun, Zhu, Zijing, Fan, Yanqin, Lin, Qiaoxuan, Ding, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721005/
https://www.ncbi.nlm.nih.gov/pubmed/34988075
http://dx.doi.org/10.3389/fcell.2021.769213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721005/
https://www.ncbi.nlm.nih.gov/pubmed/34988075
http://dx.doi.org/10.3389/fcell.2021.769213

Ejemplares similares