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Mfn2 Regulates High Glucose-Induced MAMs Dysfunction and Apoptosis in Podocytes via PERK Pathway

The endoplasmic reticulum (ER) stress and mitochondrial dysfunction in high glucose (HG)-induced podocyte injury have been demonstrated to the progression of diabetic kidney disease (DKD). However, the pathological mechanisms remain equivocal. Mitofusin2 (Mfn2) was initially identified as a dynamin-...

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Detalles Bibliográficos
Autores principales:	Cao, Yun, Chen, Zhaowei, Hu, Jijia, Feng, Jun, Zhu, Zijing, Fan, Yanqin, Lin, Qiaoxuan, Ding, Guohua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721005/ https://www.ncbi.nlm.nih.gov/pubmed/34988075 http://dx.doi.org/10.3389/fcell.2021.769213

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