IFNγ and iNOS-Mediated Alterations in the Bone Marrow and Thymus and Its Impact on Mycobacterium avium-Induced Thymic Atrophy

Disseminated infection with the high virulence strain of Mycobacterium avium 25291 leads to progressive thymic atrophy. We previously showed that M. avium-induced thymic atrophy results from increased glucocorticoid levels that synergize with nitric oxide (NO) produced by interferon gamma (IFNγ) act...

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Detalles Bibliográficos
Autores principales: Barreira-Silva, Palmira, Melo-Miranda, Rita, Nobrega, Claudia, Roque, Susana, Serre-Miranda, Cláudia, Borges, Margarida, Armada, Gisela, de Sá Calçada, Daniela, Behar, Samuel M., Appelberg, Rui, Correia-Neves, Margarida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721011/
https://www.ncbi.nlm.nih.gov/pubmed/34987496
http://dx.doi.org/10.3389/fimmu.2021.696415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721011/
https://www.ncbi.nlm.nih.gov/pubmed/34987496
http://dx.doi.org/10.3389/fimmu.2021.696415

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