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Protective Effect of Fluorofenidone Against Acute Lung Injury Through Suppressing the MAPK/NF-κB Pathway

Acute lung injury (ALI) is a severe disease that presents serious damage and excessive inflammation in lungs with high mortality without effective pharmacological therapy. Fluorofenidone (AKFPD) is a novel pyridone agent that has anti-fibrosis, anti-inflammation, and other pharmacological activities...

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Detalles Bibliográficos
Autores principales: Lv, Xin, Yao, Tingting, He, Rongling, He, Yijun, Li, Mengyu, Han, Yuanyuan, Zhang, Yan, Long, Lingzhi, Jiang, Guoliang, Cheng, Xiaoyun, Xie, Yanyun, Huang, Ling, Peng, Zhangzhe, Hu, Gaoyun, Li, Qianbin, Tao, Lijian, Meng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721041/
https://www.ncbi.nlm.nih.gov/pubmed/34987397
http://dx.doi.org/10.3389/fphar.2021.772031