The GLP-1R Agonist Exendin-4 Attenuates Hyperglycemia-Induced Chemoresistance in Human Endometrial Cancer Cells Through ROS-Mediated Mitochondrial Pathway

This study aimed to assess the effects of the antidiabetic drug Exendin-4 (Exe-4), a GLP-1 receptor agonist, on the response of human endometrial cancer cells to chemotherapy under high glucose (HG) conditions. Cell viability was detected using a cell counting kit (CCK)-8. Cell apoptosis and reactiv...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Cheng, Juan, Li, Jing, He, Junxian, Li, Xiaomao, Xu, Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721044/
https://www.ncbi.nlm.nih.gov/pubmed/34988025
http://dx.doi.org/10.3389/fonc.2021.793530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721044/
https://www.ncbi.nlm.nih.gov/pubmed/34988025
http://dx.doi.org/10.3389/fonc.2021.793530

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