Activation of Sphingomyelinase-Ceramide-Pathway in COVID-19 Purposes Its Inhibition for Therapeutic Strategies

Effective treatment strategies for severe coronavirus disease (COVID-19) remain scarce. Hydrolysis of membrane-embedded, inert sphingomyelin by stress responsive sphingomyelinases is a hallmark of adaptive responses and cellular repair. As demonstrated in experimental and observational clinical stud...

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Detalles Bibliográficos
Autores principales: Abusukhun, Murad, Winkler, Martin S., Pöhlmann, Stefan, Moerer, Onnen, Meissner, Konrad, Tampe, Björn, Hofmann-Winkler, Heike, Bauer, Michael, Gräler, Markus H., Claus, Ralf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721106/
https://www.ncbi.nlm.nih.gov/pubmed/34987511
http://dx.doi.org/10.3389/fimmu.2021.784989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721106/
https://www.ncbi.nlm.nih.gov/pubmed/34987511
http://dx.doi.org/10.3389/fimmu.2021.784989

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