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Adaptive Immune Response Signaling Is Suppressed in Ly6C(high) Monocyte but Upregulated in Monocyte Subsets of ApoE (-/-) Mice — Functional Implication in Atherosclerosis

RATIONALE: Inflammatory monocyte (MC) subset differentiation is a major feature in tissue inflammatory and atherosclerosis. The underlying molecular mechanism remains unclear. OBJECTIVE: This study aims to explore molecule targets and signaling which determinate immunological features in MC subsets....

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Detalles Bibliográficos
Autores principales: Yang, Pingping, Wu, Qinghua, Sun, Lizhe, Fang, Pu, Liu, Lu, Ji, Yong, Park, Joon-Young, Qin, Xuebin, Yang, Xiaofeng, Wang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721109/
https://www.ncbi.nlm.nih.gov/pubmed/34987524
http://dx.doi.org/10.3389/fimmu.2021.809208