Exploring K( v )1.2 Channel Inactivation Through MD Simulations and Network Analysis

The KCNA2 gene encodes the K( v )1.2 channel, a mammalian Shaker-like voltage-gated K(+) channel, whose defections are linked to neuronal deficiency and childhood epilepsy. Despite the important role in the kinetic behavior of the channel, the inactivation remained hereby elusive. Here, we studied t...

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Detalles Bibliográficos
Autores principales: Costa, Flavio, Guardiani, Carlo, Giacomello, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721119/
https://www.ncbi.nlm.nih.gov/pubmed/34988118
http://dx.doi.org/10.3389/fmolb.2021.784276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721119/
https://www.ncbi.nlm.nih.gov/pubmed/34988118
http://dx.doi.org/10.3389/fmolb.2021.784276

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