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Exploring K( v )1.2 Channel Inactivation Through MD Simulations and Network Analysis
The KCNA2 gene encodes the K( v )1.2 channel, a mammalian Shaker-like voltage-gated K(+) channel, whose defections are linked to neuronal deficiency and childhood epilepsy. Despite the important role in the kinetic behavior of the channel, the inactivation remained hereby elusive. Here, we studied t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721119/ https://www.ncbi.nlm.nih.gov/pubmed/34988118 http://dx.doi.org/10.3389/fmolb.2021.784276 |