Dysregulation of the Retromer Complex in Brain Endothelial Cells Results in Accumulation of Phosphorylated Tau

INTRODUCTION: Transport through endothelial cells of the blood–brain barrier (BBB) involves a complex group of structures of the endo-lysosome system such as early and late endosomes, and the retromer complex system. Studies show that neuronal dysregulation of the vacuolar protein sorting 35 (VPS35)...

Descripción completa

Detalles Bibliográficos
Autores principales: Filippone, Alessia, Smith, Tiffany, Pratico, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721160/
https://www.ncbi.nlm.nih.gov/pubmed/35002279
http://dx.doi.org/10.2147/JIR.S342096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721160/
https://www.ncbi.nlm.nih.gov/pubmed/35002279
http://dx.doi.org/10.2147/JIR.S342096

Ejemplares similares