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Dysregulation of the Retromer Complex in Brain Endothelial Cells Results in Accumulation of Phosphorylated Tau
INTRODUCTION: Transport through endothelial cells of the blood–brain barrier (BBB) involves a complex group of structures of the endo-lysosome system such as early and late endosomes, and the retromer complex system. Studies show that neuronal dysregulation of the vacuolar protein sorting 35 (VPS35)...
Autores principales: | Filippone, Alessia, Smith, Tiffany, Pratico, Domenico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721160/ https://www.ncbi.nlm.nih.gov/pubmed/35002279 http://dx.doi.org/10.2147/JIR.S342096 |
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