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Genetic Ablation of the Mitochondrial Calcium Uniporter (MCU) Does not Impair T Cell-Mediated Immunity In Vivo

T cell activation and differentiation is associated with metabolic reprogramming to cope with the increased bioenergetic demand and to provide metabolic intermediates for the biosynthesis of building blocks. Antigen receptor stimulation not only promotes the metabolic switch of lymphocytes but also...

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Detalles Bibliográficos
Autores principales: Wu, Hao, Brand, Benjamin, Eckstein, Miriam, Hochrein, Sophia M., Shumanska, Magdalena, Dudek, Jan, Nickel, Alexander, Maack, Christoph, Bogeski, Ivan, Vaeth, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721163/
https://www.ncbi.nlm.nih.gov/pubmed/34987384
http://dx.doi.org/10.3389/fphar.2021.734078