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Genetic Ablation of the Mitochondrial Calcium Uniporter (MCU) Does not Impair T Cell-Mediated Immunity In Vivo
T cell activation and differentiation is associated with metabolic reprogramming to cope with the increased bioenergetic demand and to provide metabolic intermediates for the biosynthesis of building blocks. Antigen receptor stimulation not only promotes the metabolic switch of lymphocytes but also...
Autores principales: | Wu, Hao, Brand, Benjamin, Eckstein, Miriam, Hochrein, Sophia M., Shumanska, Magdalena, Dudek, Jan, Nickel, Alexander, Maack, Christoph, Bogeski, Ivan, Vaeth, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721163/ https://www.ncbi.nlm.nih.gov/pubmed/34987384 http://dx.doi.org/10.3389/fphar.2021.734078 |
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