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Cartilage degeneration is associated with activation of the PI3K/AKT signaling pathway in a growing rat experimental model of developmental trochlear dysplasia

INTRODUCTION: Trochlear dysplasia is a commonly encountered lower extremity deformity in humans. However, the molecular mechanism of cartilage degeneration in trochlear dysplasia is unclear thus far. OBJECTIVES: The PI3K/AKT signaling pathway is known to be important for regulating the pathophysiolo...

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Detalles Bibliográficos
Autores principales: Lin, Wei, Kang, Huijun, Niu, Yingzhen, Niu, Jinghui, Fan, Chongyi, Feng, Xunkai, Wang, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721235/
https://www.ncbi.nlm.nih.gov/pubmed/35003796
http://dx.doi.org/10.1016/j.jare.2021.04.006