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Fangchinoline diminishes STAT3 activation by stimulating oxidative stress and targeting SHP-1 protein in multiple myeloma model

INTRODUCTION: The development of cancer generally occurs as a result of various deregulated molecular mechanisms affecting the genes that can control normal cellular growth. Signal transducer and activator of transcription 3 (STAT3) pathway, once aberrantly activated can promote carcinogenesis by re...

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Detalles Bibliográficos
Autores principales: Jung, Young Yun, Ha, In Jin, Um, Jae-Young, Sethi, Gautam, Ahn, Kwang Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721253/
https://www.ncbi.nlm.nih.gov/pubmed/35024200
http://dx.doi.org/10.1016/j.jare.2021.03.008