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H(2)S donating corticosteroids: Design, synthesis and biological evaluation in a murine model of asthma
INTRODUCTION: Hydrogen sulfide (H(2)S) is a fundamental biological endogenous gas-mediator in the respiratory system. It regulates pivotal patho-physiological processes such as oxidative stress, pulmonary circulation, airway tone and inflammation. OBJECTIVES: We herein describe the design and synthe...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721254/ https://www.ncbi.nlm.nih.gov/pubmed/35024201 http://dx.doi.org/10.1016/j.jare.2021.05.008 |