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Case Report: Response to Almonertinib in a Patient With Metastatic NSCLC Resistant to Osimertinib due to Acquired EGFR L718Q Mutation

Osimertinib shows strong clinical activity in first- and second-line treatment of nonsmall-cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations, especially EGFR T790M. However, when patients develop resistance, there is currently no definite postosimertinib treatm...

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Detalles Bibliográficos
Autores principales: Shen, Gang, Shi, Lei, Tian, Xin, Huang, Depei, Chen, Hao, Gao, Chan, Shen, Xudong, Zhang, Hushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721274/
https://www.ncbi.nlm.nih.gov/pubmed/34987382
http://dx.doi.org/10.3389/fphar.2021.731895