TRAIL-R1-Targeted CAR-T Cells Exhibit Dual Antitumor Efficacy

Tumor necrosis factor–related apoptosis-inducing ligand receptor 1 (TRAIL-R1) has limited expression in normal tissues but was highly expressed in various types of tumors, making it an attractive target for cancer immunotherapy. Here, we utilized the single-chain variable fragment (scFv) from our pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Nai, Yaru, Du, Li, Shen, Meiying, Li, Tingting, Huang, Jingjing, Han, Xiaojian, Luo, Feiyang, Wang, Wang, Pang, Da, Jin, Aishun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721281/
https://www.ncbi.nlm.nih.gov/pubmed/34988114
http://dx.doi.org/10.3389/fmolb.2021.756599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721281/
https://www.ncbi.nlm.nih.gov/pubmed/34988114
http://dx.doi.org/10.3389/fmolb.2021.756599

Ejemplares similares