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TRAIL-R1-Targeted CAR-T Cells Exhibit Dual Antitumor Efficacy

Tumor necrosis factor–related apoptosis-inducing ligand receptor 1 (TRAIL-R1) has limited expression in normal tissues but was highly expressed in various types of tumors, making it an attractive target for cancer immunotherapy. Here, we utilized the single-chain variable fragment (scFv) from our pr...

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Detalles Bibliográficos
Autores principales:	Nai, Yaru, Du, Li, Shen, Meiying, Li, Tingting, Huang, Jingjing, Han, Xiaojian, Luo, Feiyang, Wang, Wang, Pang, Da, Jin, Aishun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721281/ https://www.ncbi.nlm.nih.gov/pubmed/34988114 http://dx.doi.org/10.3389/fmolb.2021.756599

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