Nano-Honokiol ameliorates the cognitive deficits in TgCRND8 mice of Alzheimer’s disease via inhibiting neuropathology and modulating gut microbiota

INTRODUCTION: Honokiol (HO) exerts neuroprotective effects in several animal models of Alzheimer’s disease (AD), but the poor dissolution hampers its bioavailability and therapeutic efficacy. OBJECTIVES: A novel honokiol nanoscale drug delivery system (Nano-HO) with smaller size and excellent stabil...

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Detalles Bibliográficos
Autores principales: Qu, Chang, Li, Qiao-Ping, Su, Zi-Ren, Ip, Siu-Po, Yuan, Qiu-Ju, Xie, You-Liang, Xu, Qing-Qing, Yang, Wen, Huang, Yan-Feng, Xian, Yan-Fang, Lin, Zhi-Xiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Pharmaceutical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721355/
https://www.ncbi.nlm.nih.gov/pubmed/35024199
http://dx.doi.org/10.1016/j.jare.2021.03.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721355/
https://www.ncbi.nlm.nih.gov/pubmed/35024199
http://dx.doi.org/10.1016/j.jare.2021.03.012

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