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Nano-Honokiol ameliorates the cognitive deficits in TgCRND8 mice of Alzheimer’s disease via inhibiting neuropathology and modulating gut microbiota
INTRODUCTION: Honokiol (HO) exerts neuroprotective effects in several animal models of Alzheimer’s disease (AD), but the poor dissolution hampers its bioavailability and therapeutic efficacy. OBJECTIVES: A novel honokiol nanoscale drug delivery system (Nano-HO) with smaller size and excellent stabil...
Autores principales: | Qu, Chang, Li, Qiao-Ping, Su, Zi-Ren, Ip, Siu-Po, Yuan, Qiu-Ju, Xie, You-Liang, Xu, Qing-Qing, Yang, Wen, Huang, Yan-Feng, Xian, Yan-Fang, Lin, Zhi-Xiu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721355/ https://www.ncbi.nlm.nih.gov/pubmed/35024199 http://dx.doi.org/10.1016/j.jare.2021.03.012 |
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