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Tolerance and Pharmacokinetics of Recombinant Human Endostatin Administered as Single-Dose or Multiple-Dose Infusions in Patients With Advanced Solid Tumors: A Phase I Clinical Trial

Objective: This study aimed to investigate the tolerance and pharmacokinetic characteristics of recombinant human endostatin (rh-endostatin) administered as single-dose or multiple-dose infusions in patients with advanced solid tumors. Methods: This phase I trial was designed as a single-center, sin...

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Detalles Bibliográficos
Autores principales: Wang, Xu, Shi, Yehui, Jia, Yongsheng, Zhao, Weipeng, Zhang, Li, Bai, Guiying, Ren, Yulin, Chen, Yong-Zi, Tong, Zhongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721376/
https://www.ncbi.nlm.nih.gov/pubmed/34931914
http://dx.doi.org/10.1177/15330338211064434