Drug-Induced Hyperglycemia as a Potential Contributor to Translational Failure of Uncompetitive NMDA Receptor Antagonists

Hyperglycemia is a comorbidity in 60–80% of stroke patients; nevertheless, neuroprotective drugs like NMDA receptor (NMDAR) antagonists are typically assessed in normoglycemic animals at the preclinical stage before they are approved to enter clinical trials. Interestingly, as a possible explanation...

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Detalles Bibliográficos
Autores principales: Wang, Eric Yuhsiang, Lai, Ted Weita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721515/
https://www.ncbi.nlm.nih.gov/pubmed/34862204
http://dx.doi.org/10.1523/ENEURO.0346-21.2021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721515/
https://www.ncbi.nlm.nih.gov/pubmed/34862204
http://dx.doi.org/10.1523/ENEURO.0346-21.2021

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