Analysis of L-leucine amino acid transporter species activity and gene expression by human blood brain barrier hCMEC/D3 model reveal potential LAT1, LAT4, B(0)AT2 and y(+)LAT1 functional cooperation

In the CNS, amino acid (AA) neurotransmitters and neurotransmitter precursors are subject to tight homeostatic control mediated by blood-brain barrier (BBB) solute carrier amino acid transporters (AATs). Since the BBB is composed of multiple closely apposed cell types and opportunities for human in...

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Detalles Bibliográficos
Autores principales: Taslimifar, Mehdi, Faltys, Martin, Kurtcuoglu, Vartan, Verrey, François, Makrides, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721536/
https://www.ncbi.nlm.nih.gov/pubmed/34427144
http://dx.doi.org/10.1177/0271678X211039593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721536/
https://www.ncbi.nlm.nih.gov/pubmed/34427144
http://dx.doi.org/10.1177/0271678X211039593

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