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Analysis of L-leucine amino acid transporter species activity and gene expression by human blood brain barrier hCMEC/D3 model reveal potential LAT1, LAT4, B(0)AT2 and y(+)LAT1 functional cooperation
In the CNS, amino acid (AA) neurotransmitters and neurotransmitter precursors are subject to tight homeostatic control mediated by blood-brain barrier (BBB) solute carrier amino acid transporters (AATs). Since the BBB is composed of multiple closely apposed cell types and opportunities for human in...
Autores principales: | Taslimifar, Mehdi, Faltys, Martin, Kurtcuoglu, Vartan, Verrey, François, Makrides, Victoria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721536/ https://www.ncbi.nlm.nih.gov/pubmed/34427144 http://dx.doi.org/10.1177/0271678X211039593 |
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