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Concentration-Dependent Effects of Cobalt and Chromium Ions on Osteoarthritic Chondrocytes

OBJECTIVE: Cobalt and chromium (CoCr) ions from metal implants are released into the joint due to biotribocorrosion, inducing apoptosis and altering gene expression in various cell types. Here, we asked whether CoCr ions concentration-dependently changed viability, transcriptional activity, and infl...

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Detalles Bibliográficos
Autores principales: Bauer, Christoph, Stotter, Christoph, Jeyakumar, Vivek, Niculescu-Morzsa, Eugenia, Simlinger, Bojana, Rodríguez Ripoll, Manel, Klestil, Thomas, Franek, Friedrich, Nehrer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721608/
https://www.ncbi.nlm.nih.gov/pubmed/31779468
http://dx.doi.org/10.1177/1947603519889389