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Combination of a Collagen Scaffold and an Adhesive Hyaluronan-Based Hydrogel for Cartilage Regeneration: A Proof of Concept in an Ovine Model

OBJECTIVE: Hyaluronic acid–transglutaminase (HA-TG) is an enzymatically crosslinkable adhesive hydrogel with chondrogenic properties demonstrated in vitro and in an ectopic mouse model. In this study, we investigated the feasibility of using HA-TG in a collagen scaffold to treat chondral lesions in...

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Detalles Bibliográficos
Autores principales: Levinson, Clara, Cavalli, Emma, von Rechenberg, Brigitte, Zenobi-Wong, Marcy, Darwiche, Salim E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721621/
https://www.ncbi.nlm.nih.gov/pubmed/33511860
http://dx.doi.org/10.1177/1947603521989417