IL4-10 Fusion Protein Shows DMOAD Activity in a Rat Osteoarthritis Model

OBJECTIVE: Ideally, disease-modifying osteoarthritis (OA) drugs (DMOAD) should combine chondroprotective, anti-inflammatory, and analgesic effects in a single molecule. A fusion protein of interleukin-4 (IL-4) and IL-10 (IL4-10 FP) possesses these combined effects. In this study, the DMOAD activity...

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Detalles Bibliográficos
Autores principales: van Helvoort, E.M., de Visser, H.M., Lafeber, F.P.J.G., Coeleveld, K., Versteeg, S., Weinans, H.H, Popov-Celeketic, J., Eijkelkamp, N., Mastbergen, S.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Clinical Research papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721682/
https://www.ncbi.nlm.nih.gov/pubmed/34159843
http://dx.doi.org/10.1177/19476035211026736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721682/
https://www.ncbi.nlm.nih.gov/pubmed/34159843
http://dx.doi.org/10.1177/19476035211026736

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