Inhibiting spinal secretory phospholipase A(2) after painful nerve root injury attenuates established pain and spinal neuronal hyperexcitability by altering spinal glutamatergic signaling

Neuropathic injury is accompanied by chronic inflammation contributing to the onset and maintenance of pain after an initial insult. In addition to their roles in promoting immune cell activation, inflammatory mediators like secretory phospholipase A(2) (sPLA(2)) modulate nociceptive and excitatory...

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Detalles Bibliográficos
Autores principales: Kartha, Sonia, Ghimire, Prabesh, Winkelstein, Beth A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721705/
https://www.ncbi.nlm.nih.gov/pubmed/34919471
http://dx.doi.org/10.1177/17448069211066221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721705/
https://www.ncbi.nlm.nih.gov/pubmed/34919471
http://dx.doi.org/10.1177/17448069211066221

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