Cargando…

PV-specific loss of the transcriptional coactivator PGC-1α slows down the evolution of epileptic activity in an acute ictogenic model

The transcriptional coactivator, PGC-1α (peroxisome proliferator-activated receptor γ coactivator 1α), plays a key role in coordinating energy requirement within cells. Its importance is reflected in the growing number of psychiatric and neurological conditions that have been associated with reduced...

Descripción completa

Detalles Bibliográficos
Autores principales: Mackenzie-Gray Scott, Connie, Parrish, R. Ryley, Walsh, Darren, Racca, Claudia, Cowell, Rita M., Trevelyan, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721902/
https://www.ncbi.nlm.nih.gov/pubmed/34788174
http://dx.doi.org/10.1152/jn.00295.2021