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PV-specific loss of the transcriptional coactivator PGC-1α slows down the evolution of epileptic activity in an acute ictogenic model
The transcriptional coactivator, PGC-1α (peroxisome proliferator-activated receptor γ coactivator 1α), plays a key role in coordinating energy requirement within cells. Its importance is reflected in the growing number of psychiatric and neurological conditions that have been associated with reduced...
Autores principales: | Mackenzie-Gray Scott, Connie, Parrish, R. Ryley, Walsh, Darren, Racca, Claudia, Cowell, Rita M., Trevelyan, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721902/ https://www.ncbi.nlm.nih.gov/pubmed/34788174 http://dx.doi.org/10.1152/jn.00295.2021 |
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