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Assessment of bidirectional relationships between 98 genera of the human gut microbiota and amyotrophic lateral sclerosis: a 2-sample Mendelian randomization study

BACKGROUND: Growing evidence suggests a mutual interaction between gut microbiome alterations and ALS pathogenesis. However, previous studies were susceptible to potential confounding factors and reverse causation bias, likely leading to inconsistent and biased results. OBJECTIVES: To decipher the p...

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Detalles Bibliográficos
Autores principales: Zhang, Linjing, Zhuang, Zhenhuang, Zhang, Gan, Huang, Tao, Fan, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721912/
https://www.ncbi.nlm.nih.gov/pubmed/34979977
http://dx.doi.org/10.1186/s12883-021-02522-z