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Robust normalization and transformation techniques for constructing gene coexpression networks from RNA-seq data

BACKGROUND: Constructing gene coexpression networks is a powerful approach for analyzing high-throughput gene expression data towards module identification, gene function prediction, and disease-gene prioritization. While optimal workflows for constructing coexpression networks, including good choic...

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Detalles Bibliográficos
Autores principales: Johnson, Kayla A., Krishnan, Arjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721966/
https://www.ncbi.nlm.nih.gov/pubmed/34980209
http://dx.doi.org/10.1186/s13059-021-02568-9