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Pancreatic fibrosis, acinar atrophy and chronic inflammation in surgical specimens associated with survival in patients with resectable pancreatic ductal adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC), one of the most lethal malignancies, is increasing in incidence. However, the stromal reaction pathophysiology and its role in PDAC development remain unknown. We, therefore, investigated the potential role of histological chronic pancreatitis fin...

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Detalles Bibliográficos
Autores principales: Korpela, Taija, Ristimäki, Ari, Udd, Marianne, Vuorela, Tiina, Mustonen, Harri, Haglund, Caj, Kylänpää, Leena, Seppänen, Hanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721973/
https://www.ncbi.nlm.nih.gov/pubmed/34980011
http://dx.doi.org/10.1186/s12885-021-09080-0