Monitoring of post-transplant MLL-PTD as minimal residual disease can predict relapse after allogeneic HSCT in patients with acute myeloid leukemia and myelodysplastic syndrome

BACKGROUND: The mixed-lineage leukemia (MLL) gene is located on chromosome 11q23. The MLL gene can be rearranged to generate partial tandem duplications (MLL-PTD), which occurs in about 5-10% of acute myeloid leukemia (AML) with a normal karyotype and in 5-6% of myelodysplastic syndrome (MDS) patien...

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Detalles Bibliográficos
Autores principales: Kong, Jun, Gao, Meng-Ge, Qin, Ya-Zhen, Wang, Yu, Yan, Chen-Hua, Sun, Yu-Qian, Chang, Ying-Jun, Xu, Lan-Ping, Zhang, Xiao-Hui, Liu, Kai-Yan, Huang, Xiao-Jun, Zhao, Xiao-Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721994/
https://www.ncbi.nlm.nih.gov/pubmed/34979982
http://dx.doi.org/10.1186/s12885-021-09051-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8721994/
https://www.ncbi.nlm.nih.gov/pubmed/34979982
http://dx.doi.org/10.1186/s12885-021-09051-5

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