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CRISPR guides induce gene silencing in plants in the absence of Cas

BACKGROUND: RNA-targeting CRISPR-Cas can provide potential advantages over DNA editing, such as avoiding pleiotropic effects of genome editing, providing precise spatiotemporal regulation, and expanded function including antiviral immunity. RESULTS: Here, we report the use of CRISPR-Cas13 in plants...

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Detalles Bibliográficos
Autores principales: Sharma, Veerendra Kumar, Marla, Sandeep, Zheng, Wenguang, Mishra, Divya, Huang, Jun, Zhang, Wei, Morris, Geoffrey Preston, Cook, David Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722000/
https://www.ncbi.nlm.nih.gov/pubmed/34980227
http://dx.doi.org/10.1186/s13059-021-02586-7