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Induction of m(6)A methylation in adipocyte exosomal LncRNAs mediates myeloma drug resistance

BACKGROUND: Therapeutic resistance occurs in most patients with multiple myeloma (MM). One of the key mechanisms for MM drug resistance comes from the interaction between MM cells and adipocytes that inhibits drug-induced apoptosis in MM cells; MM cells reprogram adipocytes to morph into different c...

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Detalles Bibliográficos
Autores principales: Wang, Zhiming, He, Jin, Bach, Duc-hiep, Huang, Yung-hsing, Li, Zongwei, Liu, Huan, Lin, Pei, Yang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722039/
https://www.ncbi.nlm.nih.gov/pubmed/34980213
http://dx.doi.org/10.1186/s13046-021-02209-w