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Compression enhances invasive phenotype and matrix degradation of breast Cancer cells via Piezo1 activation

BACKGROUND: Uncontrolled growth in solid breast cancer generates mechanical compression that may drive the cancer cells into a more invasive phenotype, but little is known about how such compression affects the key events and corresponding regulatory mechanisms associated with invasion of breast can...

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Detalles Bibliográficos
Autores principales: Luo, Mingzhi, Cai, Grace, Ho, Kenneth K. Y., Wen, Kang, Tong, Zhaowen, Deng, Linhong, Liu, Allen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722159/
https://www.ncbi.nlm.nih.gov/pubmed/34979904
http://dx.doi.org/10.1186/s12860-021-00401-6