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A 37 kb region upstream of brachyury comprising a notochord enhancer is essential for notochord and tail development

The node-streak border region comprising notochord progenitor cells (NPCs) at the posterior node and neuro-mesodermal progenitor cells (NMPs) in the adjacent epiblast is the prime organizing center for axial elongation in mouse embryos. The T-box transcription factor brachyury (T) is essential for b...

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Detalles Bibliográficos
Autores principales: Schifferl, Dennis, Scholze-Wittler, Manuela, Wittler, Lars, Veenvliet, Jesse V., Koch, Frederic, Herrmann, Bernhard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722351/
https://www.ncbi.nlm.nih.gov/pubmed/34822716
http://dx.doi.org/10.1242/dev.200059