Maternal Dppa2 and Dppa4 are dispensable for zygotic genome activation but important for offspring survival

Zygotic genome activation (ZGA) represents the initiation of transcription following fertilisation. Despite its importance, we know little of the molecular events that initiate mammalian ZGA in vivo. Recent in vitro studies in mouse embryonic stem cells have revealed developmental pluripotency assoc...

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Detalles Bibliográficos
Autores principales: Kubinyecz, Oana, Santos, Fatima, Drage, Deborah, Reik, Wolf, Eckersley-Maslin, Melanie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722389/
https://www.ncbi.nlm.nih.gov/pubmed/34931676
http://dx.doi.org/10.1242/dev.200191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722389/
https://www.ncbi.nlm.nih.gov/pubmed/34931676
http://dx.doi.org/10.1242/dev.200191

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