Cargando…

A single-cell resolved cell-cell communication model explains lineage commitment in hematopoiesis

Cells do not make fate decisions independently. Arguably, every cell-fate decision occurs in response to environmental signals. In many cases, cell-cell communication alters the dynamics of the internal gene regulatory network of a cell to initiate cell-fate transitions, yet models rarely take this...

Descripción completa

Detalles Bibliográficos
Autores principales: Rommelfanger, Megan K., MacLean, Adam L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722395/
https://www.ncbi.nlm.nih.gov/pubmed/34935903
http://dx.doi.org/10.1242/dev.199779