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A single-cell resolved cell-cell communication model explains lineage commitment in hematopoiesis
Cells do not make fate decisions independently. Arguably, every cell-fate decision occurs in response to environmental signals. In many cases, cell-cell communication alters the dynamics of the internal gene regulatory network of a cell to initiate cell-fate transitions, yet models rarely take this...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722395/ https://www.ncbi.nlm.nih.gov/pubmed/34935903 http://dx.doi.org/10.1242/dev.199779 |